Dr.Vignesh T P
Purpose: To determine whether there is an association between hyperhomocysteinemia and chronic central serous chorioretinopathy (CCSC).
Methods: Patients with CCSC underwent visual acuity assessment, a complete fundus evaluation, fluorescein angiography, optical coherence tomography and serum homocysteine estimation.
Results: Nineteen patients were included in the study and all were males. Eight patients had bilateral CCSC and 11 patients had unilateral CCSC. The mean serum homocysteine level was 9.55 μmol/l and 4 patients (21%) had mild elevation of serum homocysteine (>15 μmol/l).
Conclusion: Our study has shown that there exists an association between mild hyperhomocysteinemia and CCSC, however a larger study is warranted.
Background: Stress is known to increase serum homocysteine levels and as Central serous chorioretinopathy (CSC) is associated with stress and type A personality, we wanted to study the serum homocysteine levels in subjects with chronic CSC.


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