Dr.Anushri Agrawal
AIM: To quantify cells in the AC by OCT in a cross-sectional study.
METHOD: An SD-OCT was used to image AC of uveitis subjects. The scan was divided into central, superior, and inferior regions. A computer algorithm was used to automatically identify particles in OCT images and then compared with clinical grading.
RESULT: AC cells were visualized as reflective spots. In 25 nongranulomatous and 15 granulomatous eyes, the cell counts correlated well with slit-lamp grades in all three regions (Spearman’s rho coefficient: >0.67). The average cell count was 3.6 cells/grade in nongranulomatous eyes and 1.9 cells/grade in granulomatous eyes. OCT revealed significant amounts of inferior AC cells in 5 of 16 quiescent uveitis eyes (mean 7).
CONCLUSION: The OCT cell counts correlated well with clinical grading, and particles in the inferior AC missed clinically were detected by OCT. OCT can be a valuable tool for diagnosis and management of anterior uveitis especially in patients with hazy cornea.
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