Dr.KUNAL MANDLIK
PURPOSE: To report a series of cases of ocular infections caused by a rare fungus, Scedosporium apiospermum, in a South Indian population.
METHODS: Retrospective study of medical records of thirteen patients detected with culture-positive Scedosporium apiospermum induced keratitis, scleritis and endophthalmitis between January 2011 and March 2016 was done. The main parameters evaluated in this study were predisposing factors, treatment modality used and final outcome of various treatment modalities.
RESULTS: Keratitis (eleven cases, 84.6%) was most common followed by sclerokeratitis (two cases, 15.3%). 9 of 11 keratitis cases (69.2%) responded well to natamycin medical therapy. Both the cases which presented with sclerokeratitis progressed to panophthalmitis and evisceration.
CONCLUSIONS: Scedosporium cases which showed keratitis alone responded well to medical therapy which included Natamycin as the primary drug. Cases which involved the sclera showed grave prognosis.
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