Dr.Navneet Mehrotra
Aim: To describe effects of anti-VEGF treatment in eyes with choroidal neovascularisation (CNV) on optical coherence tomography angiography (OCT-A).
Method: Patients (n=30) undergoing anti-VEGF injections were examined with OCT-A and followed up on day 7, 30 and 60 post injections. Comparisons of scans were done exactly at the same landmarked site of the pathology.
Results: All eyes showed reduction in fine vessel density in the neovascular tuft. In 12 eyes, decrease in the area of CNV with shrinkage of blood vessels at the edge of the lesion was noted. Central vessels and the perilesional halo persisted. Recurrences in 4 eyes revealed small tufts of new sprouting seeming to originate from the central branches.
Conclusion: OCT-A may allow direct visualisation and non-invasive analysis of CNV networks and their remodelling during anti-VEGF treatment follow-up, aiding for treatment decision.
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