Dr.Aditya Maitray
AIR encompasses carcinoma associated retinopathy, melanoma associated retinopathy, paraneoplastic vitelliform maculopathy and nonparaneoplastic AIR(npAIR). Anti-retinal antibodies causing photoreceptor damage are sin-qua-non of AIR. Diagnosis requires high index of suspicion. Subacute, relentless visual loss often occurs. There are no published reports of AIR from Indian subcontinent. We report a case of a 34y old female presenting with photopsia and floaters since 2 months. BCVA was 6/6 in OU. There was granular RPE alterations in peripapillary and mid-peripheral fundus. ERG showed rod-cone dysfunction. Multifocal ERG showed reduced foveal, parafoveal and perifoveal ring responses. Visual fields showed marked constriction. Uveitic work up was unremarkable. AIR was suspected. PET body scan was unremarkable. Serology for antiretinal antibodies was positive by western blot ELISA. She was started on immunomodulatory therapy and oral steroids. Visual fields showed improvement over 3 weeks.
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